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	Provedor de dados BJID (2) Autor Azevedo,Maria Isabel (2) Alves,Sydney Hartz (1) Denardi,Laura Bedin (1) Goldani,Luciano Z. (1) Kubiça,Thaís Felli (1) Oliveira,Vanessa (1) Santurio,Janio Morais (1) Severo,Luiz Carlos (1) Wirth,Fernanda (1) Mais... Palavra-chave Brazil (1) Cryptococcus (1) Epidemiology (1) FK506 (1) Genotypes (1) Molecular types (1) Resistance (1) Susceptibility (1) Synergism (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2018 (1) 2016 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates BJID Kubiça,Thaís Felli; Denardi,Laura Bedin; Azevedo,Maria Isabel; Oliveira,Vanessa; Severo,Luiz Carlos; Santurio,Janio Morais; Alves,Sydney Hartz. ABSTRACT The antifungal activity of tacrolimus in combination with antifungal agents against different fungal species has been previously reported. Here we report the in vitro interactions between tacrolimus and amphotericin B, fluconazole, itraconazole, and caspofungin against 30 clinical isolates of both fluconazole-susceptible and fluconazole-resistant Trichosporon asahii. For these analyses, we used the broth microdilution method based on the M27-A3 technique and checkerboard microdilution method. Tacrolimus showed no activity against T. asahii strains (minimal inhibitory concentrations, MICs > 64.0 µg mL−1). However, a larger synergistic interaction was observed by the combinations tacrolimus + amphotericin B (96.67%) and tacrolimus + caspofungin... Tipo: Info:eu-repo/semantics/article Palavras-chave: Susceptibility; FK506; Resistance; Synergism. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600539 Molecular types of Cryptococcus species isolated from patients with cryptococcal meningitis in a Brazilian tertiary care hospital BJID Wirth,Fernanda; Azevedo,Maria Isabel; Goldani,Luciano Z.. ABSTRACT There are limited data on the molecular epidemiology of cryptococcosis in Brazil. Here, we report on the identification of the molecular pattern of the Cryptococcus species that caused meningitis in patients admitted in a Brazilian reference tertiary care hospital, and review the published studies addressing the molecular epidemiology of Cryptococcus in Brazil. Our study has shown the predominance of molecular type VNII in HIV-infected patients with cryptococcal meningoencephalitis. Molecular types VNII and VGII were occasionally detected in HIV-infected and non-infected patients with meningoencephalitis. In contrast, previous studies have shown that several regions exhibited a high prevalence of the VNI molecular type and sporadic cases of the... Tipo: Info:eu-repo/semantics/other Palavras-chave: Cryptococcus; Genotypes; Molecular types; Epidemiology; Brazil. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600495 Registros recuperados: 2 Primeira ... 1 ... Última

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